Aditi redkar biography of georgetown
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ACL Rolling Review
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34th Annual Meeting & Pre-Conference Programs of the Society for Immunotherapy of Cancer (SITC 2019): part 2
Poster Presentations
Biomarkers, Immune Monitoring, and Novel Technologies
P501 Dietary deprivation of non-essential amino acids improves anti-PD-1 immunotherapy in murine colon cancer
Zehui Li, PhD, Grace Yang, PhD, Shuang Zhou, PhD, Xin Wang, MD, PhD, Xiyan Li, PhD
Filtricine, Inc., Santa Clara, CA, United States
Correspondence: Xin Wang (jimmyxinwang@filtricine.com), Xiyan Li (xiyanli@filtricine.com)
Background
Cancer cells require outside supply of some non-essential amino acids (NEAAs) to survive. Dietary deprivation of select (NEAAs) can slow down the growth of multiple solid tumors in mice, creating a new non-drug strategy in cancer treatment. However, deprivation of NEAAs could negatively impact the immune activation, an essential process for immunotherapy, because fast cell proliferation poses a higher demand for building blocks such as NEAAs. It is n
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Name: Anushka Singh
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Phone: 651-6106
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